PPE: a coin with two sides

Metachromatic leukodystrophy: two sides of a coin.

Immunotherapy with agonistic anti-CD137: two sides of a coin.

CD137 (4-1BB), a member of the TNF receptor superfamily, is an inducible T cell costimulatory receptor primarily expressed on activated CD4+ and CD8+ T cells. Agonistic monoclonal antibodies (mAbs) against CD137 greatly enhance T cell-mediated immune responses against many types of tumors and viruses. Surprisingly, these agonists also showed therapeutic effects in several autoimmune diseases. T...

Running head: TWO SIDES OF A COIN 1 Two Sides of a Coin: Analysis of An Unquiet Mind

Copper: two sides of the same coin.

The two sides of the "endotoxin coin".

Correspondence to: Dr K Radon, Unit for Occupational and Environmental Epidemiology & Net Teaching, Institute and Outpatient Clinic for Occupational and Environmental Medicine, Ziemssenstr. 1, 80336 Munich, Germany; katja. [email protected] _________________________ E ndotoxins, part of the outer membrane of Gram negative bacteria, are a potent inducer of neutrophilic airway inflammatio...